Endocrine Abstracts

Introduction: Primary hyperparathyroidism is associated with lithiasis, but this has been universally considered to refer to kidney lithiasis. Sialolithiasis as a comorbidity or result of primary hyperparathyroidism is uncommon. We report a rare case of submandibular lithiasis in a child and discuss the etiological assessment of this condition.Materials and Methods: We report a rare case of submandibular lithiasis in a child revealing primary hyperparath...

Introduction: Cortisone-induced osteoporosis (CO) is the most frequent complication of corticosteroid therapy. It is the first cause of secondary osteoporosis. The aim of this study is to clarify the characteristics of CO.Patients and Methods: We report a retrospective study of 39 cases of CO among 128 cases of osteoporosis during a 15-year period. The diagnosis of CO was based on a bone densitometry (BMD) of more than -1.5 standard deviations.<p cla...

Introduction: Osteoporosis is a generalized skeletal disease that combines a decrease in bone density with changes in bone microarchitecture. The bone is abnormally fragile and therefore the risk of fracture is high. We report the case of osteoporosis in a young woman secondary to type 1 diabetes mellitus (T1DM).Case Report: Patient A.M, 26 years old, with a history of polyglandular autoimmune syndrome type 3 since the age of 12, associating T1DM and Has...

Introduction: Inflammation has been involved in the physiopathology of diabetic ketoacidosis (DKA). Hematological inflammatory markers such as neutrophil-to-lymphocyte ratio (NLR) and white blood cell count (WBC) can serve as predictive markers for a systemic inflammatory response. This study aimed to evaluate hematological inflammatory markers in T1DM patients with DKA and without-DKA in an uninfected state and to determine their role in the prediction of DKA.<p class="ab...

Objective: To estimate the prevalence of malnutrition in elderly patients with diabetes mellitus (DM) in hospital settings.Patients and Methods: A retrospective descriptive study of 55 patients over 65 years of age who were hospitalized in the Endocrinology Department. The diagnosis of malnutrition was established according to the criteria proposed by the HAS 2021.Results: The mean age of the elderly included was 71.4&pm;6.6 years ...

Introduction: The aim of this study was to investigate the characteristics of glucocorticoid-induced diabetes (GCID) in 18 non-diabetic patients before the initiation of corticosteroid therapy.Patients and Methods: It is a retrospective study including non-diabetic hospitalized patients who developed diabetes after initiation of corticosteroid therapy.Results: Eighteen patients (5 males/13 females) with a mean age of 59.5 years wer...

Introduction: Besides insulin allergy, several other forms of insulin intolerance are possible. Adipose panniculitis (AP) is an acute form.Purpose: Describe the clinical, paraclinical and evolution of AP.Clinical case: 64-year-old patient, type 2 diabetic for 24 years on premixed human insulin for 10 years. He consults for itchy erythematous lesions at the insulin injection sites. The lesion begins with an immediate pruritus then a...

Objective: To study the carcinological factors associated with adrenal metastases (AMT) in bronchopulmonary cancer (PBC).Patients and Methods Case–control study analysing oncological data of 40 patients with PBC monitored by 18DFG PET/CT at the Nuclear Medicine Centre of Sfax, Tunisia. We compare the characteristics of 2 subgroups:G1 (n=17): patients with PBC and META (cases)G2 (n=23): ...

The aim of this study is to report a case of an unusual presentation of anaplastic thyroid carcinoma and describe its clinical, radiological and management particularities. Observation: We report the case of a 60 year-old female patient who presented with a two-week history of progressive aphagia, associated with hemoptysis. She also described recent shortness of breath, and a painless cervical mass evolving for 10 months, rapidly enlarging during the last four weeks. Her medi...

Introduction: Mitochondrial neuro-gastro-intestinal encephalopathy (MNGIE) is a rare autosomal recessive disease caused by a mutation in the TYMP gene.Patients-methods: Retrospective study including 2 cases (brother and sister) followed for MNGIE confirmed by genetic study at the endocrinology department of Sfax.Results: -> 1st case: 25-year-old man, follow-up for diabetes, dilated cardiomyopathy, renal lithiasis, MNGIE.<p ...